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This combination enables researchers to study complementary pathways: GHRH receptor activation plus selective GHS-R stimulation, with minimal off-target effects on prolactin, cortisol, or ACTH

9 Despite its severity, DN has received comparatively less attention in clinical research and therapeutic development than other diabetic complications, such as nephropathy and retinopathy, necessitating further research

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The Mitochondrial Peptide That Acts Like a Hormone The mitochondria are ancient organelles: bacterial ancestors that were co-opted by early eukaryotic cells roughly two billion years ago

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Walensky LD, Kung AL, Escher I, Malia TJ, Barbuto S, Wright RD, Wagner G, Verdine GL, Korsmeyer SJ (2004) Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix